Brain Energy System Against Neuronal Diseases

Have you ever heard of the disease of Epilepsy? The patients sometimes have seizures with convulsions and usually possible management of symptoms by drugs. However, some patients cannot be managed by drugs. Epilepsy is the energy problem of the brain. Further, it is closely related to the problem of energy substrate ATP. When using a computer, you have certainly experienced a freeze. The computer stops responding to whatever you should try. A computer has a point of informational junction. When the point is down, the computer will be frozen. As the exchange of information is performed through electric signals in a computer, communication between neurons is made possible by them. In addition, the brain has a point of information junction as a computer has. The point is pyramidal neurons, which are larger than other cells, have more dendrites, receive more input, and send out more signals. Many pyramidal neurons are excitatory in response to glutamate. These types of neurons have safety devices that suppress their electric signals. Whether or not the safety devices can be activated is the key to protecting this huge neuron (excitatory neuron). Epilepsy patients cannot activate this safety device. If the drug is not effective, there is only one way to control a special diet called the ketogenic diet. Here I talk about why ketone body can improve symptoms of epilepsy. By understanding this, I will let you know that ketone bodies may be a final hope for the brain.