Giant cell arteritis (GCA) is a chronic granulomatous vasculitis affecting predominantly women with Northern European ancestry aged 50 and older. The pathogenesis involves a complex and multifactorial process, which involves aging aspects, genetic components, and activated vascular dendritic cells. The symptomatology is nonspecific and heterogenic, including systemic manifestations, such as low-grade fever or weight loss, associated with headaches, jaw claudication, and possible ocular involvement with potential visual loss. Subclinical GCA could be concomitant with polymyalgia rheumatica. Commonly, the diagnostic methods include temporal arteries doppler ultrasounds and biopsy. The treatment consists of glucocorticoids and other immunosuppressive agents.