Grover’s disease, or transient acantholytic dermatosis, is a rare, self-limiting skin condition marked by itchy, red papules that mainly appear on the trunks of middle-aged to older adults, especially Caucasian men. First identified in 1970, this condition is neither familial nor immune-mediated, exhibiting histopathological signs of acantholysis and dyskeratosis. Although the exact etiology remains unknown, factors such as heat, sweating, certain medications, and extended bed rest have been linked to its occurrence. Diagnosis is mainly clinical, with histopathological examination utilized as needed. While the disease is typically transient and mild, more severe or persistent cases might necessitate the use of topical or systemic treatments, including corticosteroids and retinoids.

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Grover’s Disease in Older Adults

  • Dattu Vyas,
  • T. S. Dharmarajan

摘要

Grover’s disease, or transient acantholytic dermatosis, is a rare, self-limiting skin condition marked by itchy, red papules that mainly appear on the trunks of middle-aged to older adults, especially Caucasian men. First identified in 1970, this condition is neither familial nor immune-mediated, exhibiting histopathological signs of acantholysis and dyskeratosis. Although the exact etiology remains unknown, factors such as heat, sweating, certain medications, and extended bed rest have been linked to its occurrence. Diagnosis is mainly clinical, with histopathological examination utilized as needed. While the disease is typically transient and mild, more severe or persistent cases might necessitate the use of topical or systemic treatments, including corticosteroids and retinoids.