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HSCT in Low EF Patients

  • Nasim Naderi,
  • Mehdi Dehghani,
  • Seyed Hossein Mirpour Hassankiadeh

摘要

Hematopoietic stem cell transplantationHematopoietic Stem Cell Transplantation (HSCT) (HSCT) has been used as a treatment method for decades. The most common diseases in autologous hematopoietic stem cell transplantationAutologous hematopoietic stem cell transplantation (HSCT) are multiple myeloma and Hodgkin’s and non-Hodgkin lymphoma. The success rate of HSCTHematopoietic Stem Cell Transplantation (HSCT) depends on two factors including: the underlying disease and the other is the stage of the disease. ChemotherapyChemotherapy is a common method of cancerCancer treatment and is effective in cancer treatment, but adverse effects such as chemotherapy-induced cardiotoxicityChemotherapy-Induced Cardiotoxicity (CIC) are known, especially by anthracyclinesAnthracyclines and trastuzumab in HER2-positive breast cancer. RadiationRadiation therapy to the mediastinum may aggravate atherosclerosisAtherosclerosis and lead to early onset of coronary artery diseaseCoronary Artery Disease as well as valvular disease that usually affects the left side valves, as well as acute and chronic pericardial involvement may be seen after radiationRadiation therapy.