Metabolic Syndrome in HSCT

Hematopoietic cell transplantation (HCT) increases metabolic syndromeMetabolic syndrome risk that directly related to increased cardiovascular morbidity and mortality. The cause of this increase can be divided into direct or indirect injury. The direct injury is related to the cardiovascular effects of cancerCancer treatment (cardiotoxicity of the chemotherapyChemotherapy regime and/or radiotherapy before HSCTHematopoietic Stem Cell Transplantation (HSCT) and an indirect injuryCardiotoxicity includes preexistingCardiovascular disease CVRF/CVD and CV lifestyle change (i.e., deconditioning, weight gain) during and after HSC all this factor leads to an increase in metabolic syndrome that has a higher prevalence in HSCT patients, it is important to have a strategy for prevention, early detection and appropriate treatment of metabolic syndrome component in this population. In this chapter, we discuss the importance, prevention, and therapeutic strategy of metabolic syndrome inMetabolic syndrome HSCT patients.