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Sympathicolytics

  • Sylvia Masson,
  • Stéphane Bleuer-Elsner,
  • Gérard Muller,
  • Tiphaine Médam,
  • Jasmine Chevallier,
  • Emmanuel Gaultier

摘要

Sympatholytic agents include molecules that decrease noradrenergic transmission through two possible actions: blocking postsynaptic noradrenergic receptors—these are the beta-blockers—and decreasing noradrenaline release from the presynaptic neuron—these are the alpha2-agonists. This section will detail one beta-blocker propranolol and two alpha2-agonists: clonidine and dexmedetomidine. Dexmedetomidine was the only licensed veterinary medication in this drugs family, it was recently joined by tasipimidine.