Asthma Management in Obesity

People with obesity and asthma often have severe, difficult to control disease. Obesity leads to distinct physiologic changes, alters inflammatory pathways, is associated with many comorbidities, alters response to infection and environmental exposures, and modifies response to some medications. These factors affect diagnosis and phenotyping as well as management of asthma. Lifestyle and other weight loss interventions may also be helpful in this patient population. This chapter will review data guiding appropriate evaluation and management of people with obesity and asthma.