This chapter by Jamie Tyrone tells the story of an individual who went through the experience of suddenly discovering that she had a very high risk of developing Alzheimer’s disease. Ms. Tyrone has already written an award-winning book on this issue, and this chapter provides a synopsis of her experience. Since Ms. Tyrone is a nurse, she has considerable insight into the whole scenario, from being concerned about her own health, to facing the fact that she possesses two APOE-e4 genes, portending a substantial increase of risk for getting Alzheimer’s disease relative to the general population, and then how she managed her appropriately difficult concerns. Ms. Tyrone’s presentation provides considerable insight into how this extremely stressful situation has been dealt with since it became available late in the twentieth century. She outlines the difficulties the medical establishment and social culture have had in coping with this unpleasant information. Finally, Ms. Tyrone recounts how she has proactively decided to take her situation and push for health and global improvements for how people and society deal with the reality of this genetic factor and Alzheimer’s disease. The chapter provides a very interesting story with some appropriately added humor.