Progressive Supranuclear Palsy (PSP)

This chapter provides a comprehensive insight into the clinical evaluation of progressive supranuclear palsy (PSP), a neurodegenerative disorder often presenting formidable diagnostic challenges, especially in its early stages. Through a detailed exploration of history taking and rigorous examination techniques such as scrutinizing eye movements and utilizing radiologic correlates, the text delineates the subtleties and complexities involved in accurately diagnosing PSP. Particularly emphasized are the nuances of identifying and distinguishing PSP from other parkinsonian disorders, pitfalls and common misdiagnoses, and the importance of implementing palliative care resources early in the disease. The latter part of the chapter pivots towards practical and ethical considerations in management, touching upon available supportive treatments, caregiver support, and the role of end-of-life care.