Parkinson’s Disease

This chapter meticulously delves into the multifaceted arena of Parkinson’s disease (PD), traversing its natural history and broad spectrum of clinical phenotypes from early through advanced stages. Central to the narrative is the reliance on diagnostic acumen, emphasizing the cardinal features of PD—rest tremor, bradykinesia, rigidity, and postural instability—while acknowledging the non-motor features including psychological manifestations. The content envelops the diagnostic and treatment challenges faced by practitioners, weaving the complexity of varied patient presentations and progression. Accompanying videos highlight a wide spectrum of PD manifestations and responses to treatments. The natural history of PD is explored via case-based illustrations, compartmentalized into functional stages, mirroring real-world experience of patients through their journey with PD.