Acute and Chronic Lower Extremity Deep Venous Thrombosis

Deep venous thromboembolism (DVT) affects up to 900,000 patients per year in the United States with high rates of mortality and morbidity. Furthermore, more than one-third of patients will have debilitating long-term complications manifesting as post-thrombotic syndrome (PTS). Depending on the acuity of the disease, there is a spectrum of pathophysiological manifestation, clinical presentation, and treatment options. This chapter highlights the pathophysiology of acute and chronic obstructive venous disease and clinical indications. The most up-to-date treatment options, including medical and interventional, are also discussed.