Solution-Based Dosage Forms and Sterile Products
摘要
This chapter expands upon the concept of drug solubility and dissolution as it relates to dosage form design. Excipients utilized in solution-based dosage forms and parenteral products are discussed in detail, including solvents, co-solvents, antioxidants, preservatives, complexing agents, and surfactants. Special considerations that must be made for parenteral dosage forms are introduced. Lastly, a review of lyophilization and sterilization techniques is provided.