Pulmonary Drug Delivery
摘要
This chapter provides an introductory overview on concepts related to drug delivery to the lungs. Physiological barriers to lung delivery are examined, as are the mechanisms for overcoming these barriers through delivery device and formulation design. A review is provided of delivery mechanisms and design of the three major classes of pulmonary drug delivery devices (pressurized metered dose inhalers, nebulizers, and dry powder inhalers). For each class of device, appropriate formulation approaches are discussed.