Modeling Enzyme-Substrate Interaction with Localization-Delocalization Matrices

Enzymes are life’s catalysts par excellence. They are incredibly efficient and are mainly composed of protein—save prosthetic groups and/or nucleic acid components. They can enhance the rate of virtually all the chemical reactions within cells and by astronomical factors so much as to often limit reaction rates by diffusion, that is, the access of the substrate through its random walk to the active site of the enzyme. Enzymatically-catalyzed reactions are accelerated by typical factors of 108–1012.