Biodegradable Polymers for 3D Printing of Tissue Engineering Scaffolds: Challenges and Future Directions

Tissue engineeringTissue engineering holds great promise for tissue regeneration and organ replacement. The integration of biodegradable polymersBiodegradable polymers with 3D printing3D printing has revolutionized scaffold fabricationScaffold fabrication, enabling precise control over architecture and functionality. This review explores the current status and future potential of biodegradable polymersBiodegradable polymers in 3D printed tissue engineeringTissue engineering scaffolds, highlighting their fascinating properties, such as tunable mechanics and biocompatibilityBiocompatibility. We discuss various 3D printing3D printing techniques and their benefits and limitations for tissue engineeringTissue engineering applications. Current advancements in bone, cartilage, and organ tissue engineeringTissue engineering showcase the potential of 3D printed personalized approaches. Addressing challengesChallenges in scaffold resolution, materialMaterials properties, vascularization, and scalability requires innovative solutions, including multi-functional scaffolds and bioprinting. This transformative review envisions a future driven by biodegradable polymersBiodegradable polymers and 3D printing3D printing, revolutionizing regenerative medicineRegenerative medicine and offering hope to patients in need of tissue repair and regeneration.