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Synthesis of Ternary Oxide Nanoparticles of Iron, Silver, and Vanadium from Blended Extracts for Potential Tuberculosis Treatment

  • Ita E. Uwidia,
  • Esther U. Ikhuoria,
  • Rachel O. Okojie,
  • Ikhazuagbe H. Ifijen,
  • Ikechukwu D. Chikaodili

摘要

This study introduces ternary oxide nanoparticlesNanoparticles synthesized from a blend of plantain peelPlantain peel, guava leaves, and mushroom extracts, containing ironIron, silver, and vanadium. These nanoparticlesNanoparticles, with an average diameter of 291.6 nm and a polydispersity index (PDI) of 0.137, exhibit characteristics suitable for drug delivery systems, potentially enhancing tuberculosis (TB) treatment outcomes. Their irregular morphology leadsLead to aggregated formations, creating a porous structurePorous structures ideal for drug loading and controlled release, which may improve therapeutic efficacy. The incorporation of silver oxideSilver oxides nanoparticlesNanoparticles imparts antimicrobialAntimicrobial properties, offering potential inhibitionInhibition of Mycobacterium tuberculosis growth. This innovative approach, combining ironIron, silver, and vanadium oxides, presents promising avenues for TB treatment. Future research is imperative to validate the nanoparticlesNanoparticles' effectiveness and safety, highlighting their potential in advancing TB treatment strategies and infectious disease management.