Phytochemical-Mediated Green Synthesis of Silver Oxide Nanoparticles for Potential Cholera Treatment

In the pursuit of innovative choleraCholera treatment, this study explores green-synthesized silver oxideSilver oxides nanoparticlesNanoparticles (AgO NPs) using Psidium guajava LPsidium guajava L. extract as both a reducing and stabilizing agent. Extensive characterizationCharacterization through X-ray fluorescence (XRF), X-ray diffractionX-ray diffraction (XRD) (XRD), scanning electron microscopy (SEM), and dynamic light scattering (DLS) techniques confirmed the AgO NPs’ purity, crystallinity, morphology, and size distribution. The recorded average particle diameter of ~42.41 nm indicates uniformity, beneficial for applications like drug delivery and antimicrobialAntimicrobial therapy. However, the Polydispersity Index (PDI) value of 0.534 suggests some size variability. XRF analysis verified successful AgO NP synthesis with minimal ironIron contamination, suitable for biomedical applicationsBiomedical applications. XRDX-ray diffraction (XRD) spectra revealed the presence of crystalline silver oxideSilver oxides nanoparticleNanoparticles. SEM micrographs showcased an agglomerated clustered morphology, promoting interactions with cholera-causing bacteria. Psidium guajava LPsidium guajava L. extract mediated AgO NPs’ exhibit potential for choleraCholera treatment, offering purity, crystallinity, and antimicrobialAntimicrobial properties, advancing innovative treatment approaches.