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Processing and Characterization of Mg Microtubes for Biodegradable Vascular Stents

  • Joung Sik Suh,
  • Chang Dong Yim,
  • Byeong-Chan Suh,
  • Ha Sik Kim,
  • Sang Eun Lee,
  • Hwa-Chul Jung

摘要

Magnesium (Mg) alloysMagnesium alloys (Mg alloys) have attracted increasing attention as potential metallic biomaterialsBiomaterials for temporary biodegradable implants in orthopedic and vascular applications due to their mechanical, electrochemical, and biological properties. However, Mg scaffolds still face some challenges such as high degradationDegradation rate, low mechanical propertiesMechanical Properties, difficult fabrication method. ProcessingProcessing and alloying are key approaches to improving the comprehensive properties of Mg alloysMagnesium alloys (Mg alloys) for biomedical applications. This study investigated the microstructureMicrostructure, textureTexture and mechanical properties of Mg-Zn-Ca (MZ01) microtubes fabricated by two-step extrusion for biodegradable vascular stents. Direct two-step extrusion at 400 °C produced seamless MZ01 microtubes with outer diameters of 3.5 and 2.5 mm, wall thickness of 250 µm, and maximum length of 2 m. Dimensional accuracy based on roundness improved as outer diameter decreased. Increasing the extrusion ratio made grains refiner and weakened textureTexture intensity. The mechanical behavior of MZ01 microtubes was analyzed with respect to changes in microstructureMicrostructure and texture. Grain boundary strengthening and textureTexture hardening were involved in the plasticity of as-extruded MZ01 microtubes.