Protein Restriction in Aging and Disease

Protein restriction has emerged as a promising dietary intervention to promote health and combat age-related diseases. Extensive research conducted in animal models, including mice and primates, as well as data from selected clinical trials, has shed light on the molecular, cellular, and systemic responses to protein restriction. In this review, I summarize the key findings from preclinical and clinical studies, focusing on the effects of protein restriction on aging and disease prevention. Additionally, I discuss current strategies for implementing protein restriction and its potential for improving therapeutic outcomes in various pathological conditions.