错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Complexity and Enumeration in Models of Genome Rearrangement

  • Lora Bailey,
  • Heather Smith Blake,
  • Garner Cochran,
  • Nathan Fox,
  • Michael Levet,
  • Reem Mahmoud,
  • Elizabeth Bailey Matson,
  • Inne Singgih,
  • Grace Stadnyk,
  • Xinyi Wang,
  • Alexander Wiedemann

摘要

In this paper, we examine the computational complexity of enumeration in certain genome rearrangement models. We first show that the Pairwise Rearrangement problem in the Single Cut-and-Join model (Bergeron, Medvedev, & Stoye, J. Comput. Biol. 2010) is \(\#\textsf {P}\) -complete under polynomial-time Turing reductions. Next, we show that in the Single Cut or Join model (Feijao & Meidanis, IEEE ACM Trans. Comp. Biol. Bioinf. 2011), the problem of enumerating all medians ( \({\textsc {\#Median}} \) ) is logspace-computable ( \(\textsf {FL}\) ), improving upon the previous polynomial-time ( \(\textsf {FP}\) ) bound of Miklós & Smith (RECOMB 2015).