Electrospun Nanofiber Mats for Mammalian Cell Growth

Electrospinning can be used to prepare nanofiber mats from diverse polymers, polymer blends and embedded nanoparticles. Especially nanofiber mats from biopolymers promote cell growth for wound healing, tissue engineering or other biotechnological applications. These materials, however, are often not stable at high temperatures, which makes sterilization challenging. The paper discusses sterilization methods, a comparison of different biopolymer blends for cell growth, and the influence of vacuum ultraviolet irradiation (VUV) and plasma treatment on cell growth and adhesion on electrospun nanofiber mats. This mini-review thus serves as a base for researchers working on the improvement of nanofiber mats for mammalian cell growth, giving some general ideas as well as interesting special findings.