Leiomyoma

Uterine leiomyoma, also known as myomas or fibroids, is the most common benign uterine neoplasm and occur in about 70% of women [1]. Most patients with leiomyomas are asymptomatic but 2030% of patients will experience symptoms that prompt treatment [1]. These symptoms include abnormal and excessive uterine bleeding; bulk symptoms such as pelvic pressure, constipation, urinary frequency; recurrent miscarriages and infertility. Uterine myomas are benign tumors of smooth muscle cells and fibroblasts, arising from the myometrium. Their growth is dependent on estrogen and progesterone level. Risk factors associated with leiomyoma development include reproductive age, increased exposure to ovulatory cycles, nulliparity, and family history.