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Mathematical Foundations for Measurement of Communication Efficiency in the Human Brain

  • Alex Hocking,
  • Kerri Morgan,
  • Nicholas Parsons,
  • Govinda Poudel,
  • Sergiy Shelyag,
  • Julien Ugon

摘要

In this paper we provide a detailed mathematical (graph-theoretical) foundation for our newly developed metric for measurement of efficiency of communication in human brain. The metric is based on the assumption that the structural connectome paths facilitate the functional connectome. Our metric demonstrates that majority of the functional connections in the human brain can be explained by indirect functional paths. This further indicates that information transport in the human brain is a complex process, where multiple regions can participate as intermediary communication nodes.