Non-opioid Analgesic Pain Management

Liposome bupivacaine injectable suspensionLiposome bupivacaine injectable suspension (LB, EXPARELEXPAREL®, Pacira Pharmaceuticals Inc., San Diego, CA) is a long-acting bupivacaine hydrochlorideBupivacaine hydrochloride (HCL). LB is loaded in a multivesicular liposome (DepoFoam) which causes a slow and prolonged release of bupivacaine HCLBupivacaine HCL. Several studies have demonstrated that LB infiltration reduces postoperative pain after third molar extraction and/or dental implant surgeryDental implant surgery. Furthermore, LB injection reduced postoperative painNon-opioid analgesic pain management in abdominal wall augmentationAbdominal wall augmentationLB injection reduced postoperative painabdominal wall augmentation, total knee arthroplastyTotal knee arthroplastyLB injection reduced postoperative paintotal knee arthroplasty, augmentation mammaplastyAugmentation mammaplastyLB injection reduced postoperative painaugmentation mammaplasty, and/or mastectomy with tissue expanderMastectomy with tissue expanderLB injection reduced postoperative painmastectomy with tissue expander and/or implant reconstructionImplant reconstruction. The purpose of this chapter is to review the pearls and pitfalls in utilizing Liposome Bupivacaine Injectable Suspension for postoperative pain managementLiposome Bupivacaine Injectable Suspension for postoperative pain management.