Ocular Biomechanics of Glaucoma

In this study, deformations, and principal stresses in ocular tissues, especially in the optic disc, under glaucoma conditions were investigated. Four models with different parameters were developed, and their results were compared. Although the models did not yield quantitatively similar results, critical areas in the tissues were found. In these result values, the possibility of the presence of glaucoma exists, contributing to the early detection of this disease. Deformation in ocular tissues and an increase in principal stresses in the optic disc under glaucoma conditions were demonstrated. This indicates that optic nerve cells lose their mechanical properties due to the presence of stress concentrators, affecting cellular nutrition and potentially leading to cell death over time. Despite the quantitative differences, the models shared critical areas due to the geometry of the eye. These findings expand the understanding of the effects of glaucoma on ocular tissues.