In Silico Coaxial Antenna Design Applicator Optimization for Microwave Ablation Therapy in Medium Adipose Tissue Density Breast with Ductal Carcinoma In-Situ

Since 2020, breast cancer has been the one with greater incidence across the world. It is important to evaluate the possibility of the application of this minimally invasive procedure to treat the different types of premalignant lesions present in this type of cancer. Since microwave ablation therapy has been proven effective against liver and bone cancer, this research aims to assess the feasibility of an optimization method for the design of an antenna applicator that takes into consideration the effective wavelength of the breast tissue. Therefore, the computational finite element method is used to evaluate the therapy in an in-silico environment, which considers the thermodynamic, dielectric properties of the materials, modelling the response of the heat transfer in biological tissues due to microwave and the matching of the antenna. Achieving a \({\text{S}}_{11} = - 24.79{\text{ dB}}\) , SAR = 25 dB, and maximum temperature of 110 ℃ for a medium fat tissue density breast model. Inserting a 14 mm of diameter sphere with the characteristics of Ductal Carcinoma In-Situ, resulted in a \({\text{S}}_{11} = - 11.47{\text{ dB}}\) . Thus, not only maintaining the desired values for the coupling parameters, but also reaching greater ablation zones and temperatures with the lesion.