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Metabolism is not merely a background process in cellular life—it is a dynamic and responsive system that shapes the trajectory of infection, immunity, and disease. In recent years, the concept of metabolic reprogramming has emerged as a central theme in understanding host–pathogen interactions. This chapter explores how both bacterial pathogens and host cells undergo metabolic shifts during infection, revealing a complex interplay that influences virulence, immune evasion, and therapeutic outcomes.

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Metabolic Reprogramming of Bacterial and Host Pathways and Their Role in Infections

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  • 发表日期：

    2026年

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  • Vijay Soni,
  • Aditya Upadhyay

摘要

Metabolism is not merely a background process in cellular life—it is a dynamic and responsive system that shapes the trajectory of infection, immunity, and disease. In recent years, the concept of metabolic reprogramming has emerged as a central theme in understanding host–pathogen interactions. This chapter explores how both bacterial pathogens and host cells undergo metabolic shifts during infection, revealing a complex interplay that influences virulence, immune evasion, and therapeutic outcomes.