Individualised Preventive Measurements of Suboptimal Health

This chapter discusses the phases of the disease’s natural history, preventive strategies, and individualised prevention. Suboptimal Health Status (SHS) is defined as an intermediate physical state between health and disease, it is reversible and can predict or prevent non-communicable diseases (NCDs) before the onset of diseases. In preventive medicine, the subjective tool, Suboptimal Health Status Questionnaire-25 (SHSQ-25), which has been developed and validated as a reliable and robust health measurement, has been widely employed to evaluate Suboptimal Health Status (SHS) in five domains: cardiovascular system, digestive system, fatigue, immune system, and mental status. Moreover, immunoglobulin G (IgG) N-glycan patterns are suggested as one of the ideal objective measures for detecting SHS as glycosylation plays a crucial role in the inflammatory processing at the molecular level. Therefore, in order to present a deep understanding of the prevention approaches of SHS, this chapter indicates six case studies for effectively preventing the SHS defined by both subjective and objective measurements.