A Signal Conditioning Circuit with Integrated Bandgap Reference for Glucose Concentration Measurement

The paper presents development of signal conditioning circuit with integrated potentiostat for glucose measurement. The programmable transimpedance amplifier (PTIA) offers 94% linearity of output voltage. The whole architecture consumes 2.33 mW of total power. The reference potential of 0.6 V has been used for measurements. Three electrode arrangement with Ag/AgCl as reference electrode, the Pt foil as the counter electrode and a CuO/Cu0.76CO2.25O4 (copper cobaltite) coated glassy carbon electrode (GCE) filled-in used as the working electrode. The working feasibility of proposed glucose sensing architecture is tested via an emulated circuit. The second-generation current conveyor (CCII-) is implemented with the help of two AD844 ICs. The two TAs are implemented by using IC LM13700 and I-V conversion is obtained with op-amp IC LM741 and feedback resistance. The voltage ranges from 1.19 to 1.67 V has been measured corresponding to glucose concentration ranges from 18 mg/dl to 180 mg/dl.