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Bioactive Compounds and Biological Activities of Allium sativum L.

  • Amin Abbasi,
  • Kimia Dehghan Sanej,
  • Samaneh Moradi,
  • Sara Bazzaz,
  • Ali Esmaeili,
  • Kiana Ghafourian,
  • Sahar Sabahi,
  • Masoud Lahouty,
  • Sousan Akrami,
  • Ramin Aslani,
  • Hedayat Hosseini

摘要

The therapeutic properties of the dynamically bioactive components found in garlic (Allium sativum L.), including allicin, alliin, S-allylmercaptocysteine, S-trityl-L-cysteine, ajoene, diallyl sulfide, and S-allyl-cysteine, have attracted a lot of scientific interest from researchers working on related pre-clinical and clinical investigations as well as in the industrial sector. A number of issues about the bioactive chemicals in garlic that are affected by processing, as well as their possible toxicities, pharmacokinetics, and safety profile, need to be investigated in order to confirm garlic’s health benefits for humans. In this chapter, the outcomes of recent experimental and clinical reports are reviewed and the profile of bioactive compounds, metabolism pathway, bioavailability, biological/therapeutic effects, food-related applicability, methods of adulteration detection, potential toxicities, and safety profile of garlic’s derived bio-compounds will be discussed.