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Donor Selection for Adults and Pediatrics

  • Francis Ayuk,
  • Adriana Balduzzi,
  • Nina Worel

摘要

It is known that multiple factors impact transplantation outcome; the heaviest ones are disease-related (disease refractoriness, phase, clonal abnormalities, etc. in malignancies and disease type and associated rejection risk in nonmalignant diseases) and patient-related (age, comorbidities, infectious diseases/colonization, etc.). Moreover, donor-related issues and stem cell source may influence the extent of disease control and transplant-related mortality.