Protein-Ligand Interactions and Binding
摘要
Why it is important to know this material? Protein binding is implied in all biological mechanisms, and the definition of quantitative models and laws is essential to assess in a quantitative way the protein binding to small ligands,Ligand proteins, and nucleic acids. What is the key idea? Starting from molecular models, it is possible to determine the quantitative laws for protein binding. What is necessary to know already? It is essential to know how the protein structure is built and how it interacts with the environment, through a delicate interplay between stability and adaptability.