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Proteins

  • Luisa Di Paola

摘要

Why it is important to know this material? The chapter entails the central knowledge about the protein structure and function, including the thermodynamic definition of protein stability and the kinetic mechanism of enzymatic activity on the basis of the corresponding molecular mechanisms. What is the key idea? The basic idea is that the protein structure and function depends on the protein stability and interactions with the environment. What is necessary to know already? It is important to have a clear definition of the protein stability in terms of Gibbs free energy and its decomposition in enthalpic and entropic terms, and their meaning. It is also necessary to have the basics of the reaction kinetics modeling, including the effect of catalysts.