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Age-Related Pathology in Nonhuman Primates

  • Heather A. Simmons

摘要

This chapter focuses on age-related pathologies in rhesus macaques (Macaca mulatta) and common marmosets (Callithrix jacchus), two nonhuman primate species often used as models for human disease and for longitudinal studies on aging. Rhesus macaques are well-established models for age-related conditions including hypertension, diabetes, visual accommodation, amyloidosis, osteopenia, osteoporosis, sarcopenia, and frailty. Investigations of age-associated pathologies in the common marmoset include amyloidosis, diabetes, chronic renal disease, osteopenia, vision, and cognitive decline.