Digital communications have changed how people connect, share emotions, and seek support—bringing benefits and risks, particularly for individuals with psychosocial vulnerabilities and disabilities. While offering opportunities for virtual companionship and therapeutic engagement, they also introduce various challenges. This entry examines how virtual environments, especially those shaped by social media and artificial intelligence-driven applications, can heighten affective responses, disrupt self-perception, and contribute to digital dependency and compulsive engagement. Focusing on three areas, digital hostility, digital addiction, and digital bereavement, it highlights how platform design, anonymity, and immersive simulation may intensify distress and compromise socially adaptive functioning. Digital hostility can erode trust and self-worth; excessive media use may impair the ability to shift attention or adjust focus; and current artificial intelligence-mediated bereavement can entangle users in complicated grief, potentially weakening genuine social engagement. To address these issues, we emphasize a mental health framework centered on digital literacy. This approach supports healthy online and offline relationships by encouraging empathic and imaginative engagement, wholesome narrative construction, and embodied social connection. At the same time, it acknowledges that these strategies must remain context-sensitive, as identity and resilience are co-constructed through communicative interaction. By integrating insights from psychology, cognitive neuroscience, communication design, and clinical studies, this entry contributes to the ongoing dialogue about how digital systems can be more thoughtfully structured to enhance mental well-being and inclusive forms of care in an increasingly connected world. Supporting human communication and virtual environments requires not only managing the related dysfunctions but also embracing uncertainty and flexibly reinforcing the relational foundations of human existence.