This chapter discusses self-management among adolescents with Type I Diabetes (T1D). Several tasks of self-management by adolescents and their family/parents are explained. These include medication administration, glucose control and monitoring, physical activity, diet regimen, social involvement, communication, diabetic goals, and motivation. Interventions concerning T1D self-management are described. Furthermore, instruments related to diabetes self-management and the role of family/parents are explained.