This entry focuses on the recognized specific pharmaceutical care and services essential to patients with disabilities. It provides a comprehensive account of the difficulties and opportunities in delivering effective pharmaceutical care to this diverse population. It also discusses the medication needs of patients with different types of disabilities, ways to enhance the services provided by pharmacists, and appropriate communication approaches. The entry builds upon several of the patient medicine-related topics, including medication administration practices and the integrated role of pharmacists. It also gives a view to more innovative techniques likely to redefine how health care is delivered and highlights the importance of specially tailored education for pharmacists. In turn, this entry uses concepts of best practice and current information to provide healthcare professionals with the necessary information to provide integral and patient-centered therapy to persons with disabilities. In the long run, this will improve such a population’s quality of life and health.