All people, including individuals with intellectual disabilities, have a fundamental human right to spiritual identity and expression. This entry explores the rich intersections between spirituality and the lives of intellectually disabled people, examining spirituality’s contributions to coping, quality of life, and belonging among this population. Spirituality’s varied influence within educational and health care contexts relevant to intellectual disability is also examined, including the application and adaptation of standardized spiritual assessments. Spirituality is presented as a multidimensional concept with relevance to diverse human cultures, geographies, and disability identities. Multiple frameworks for spirituality—developmental, integrative, relational, and transformational—are discussed as they relate to persons with intellectual disabilities. This entry also considers how these frameworks inform current research and practice, identifying priority areas of future investigation and policy. Spirituality’s relationship to caregivers and families of people with intellectual disabilities, as well as the positive outcomes of integrating spirituality into person-centered planning, are also highlighted.