Influence of Ethnicity and Sex Bias in Systemic Sclerosis
摘要
Systemic sclerosis (SSc) is a complex autoimmune disease, in which fibrosis, vasculopathy and inflammation play pivotal pathogenetic roles. Given the high variability of disease manifestation, organ complications and prognostic outcomes, many factors have been investigated to explain this heterogeneity. This chapter is focused on the role and impact of ethnicity and sex, and how their expression influences SSc manifestations.