Clostridiodes difficile is a spore-forming organism present in normal intestinal flora that may cause infections with symptoms that range from nuisance diarrhea to life-threatening colitis. Major risk factors for C. difficile infection are hospitalization, older age, and antibiotic exposure. The organism produces a cytopathic toxin. Treatment options include: stopping the inciting agent, adjunctive agents, and surgery.

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Toxic Clostridioides difficile Colitis

  • James S. Wu,
  • Michelle D. Inkster,
  • David Hernandez Gonzalo,
  • Eric W. Willis

摘要

Clostridiodes difficile is a spore-forming organism present in normal intestinal flora that may cause infections with symptoms that range from nuisance diarrhea to life-threatening colitis. Major risk factors for C. difficile infection are hospitalization, older age, and antibiotic exposure. The organism produces a cytopathic toxin. Treatment options include: stopping the inciting agent, adjunctive agents, and surgery.