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Familial adenomatous polyposis coli is an autosomally dominant condition characterized by multiple adenomas of the large intestine. Death from colorectal cancer at an early age is inevitable without timely surgical intervention. Extraintestinal manifestations occur. A germline mutation on the long arm of chromosome 5 has been identified.

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Familial Adenomatous Polyposis Coli

  • 章节

  • 发表日期：

    2025年

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  • Carolyn L. Power,
  • Homer O. Wiland,
  • Eric W. Willis,
  • James S. Wu

摘要

Familial adenomatous polyposis coli is an autosomally dominant condition characterized by multiple adenomas of the large intestine. Death from colorectal cancer at an early age is inevitable without timely surgical intervention. Extraintestinal manifestations occur. A germline mutation on the long arm of chromosome 5 has been identified.