This chapter reviews promising preclinical and early clinical evidence that targeted bioelectrical stimulation can support osseointegration and may serve as an adjunct to existing implant therapies. Grounded in decades of research on bone’s piezoelectric properties, bioelectrical stimulation techniques, including electrical stimulation and pulsed electromagnetic fields (PEMF), have evolved from experimental concepts to promising adjuncts supported by preclinical data and small clinical studies that accelerate bone healing and bolster implant stability (Cecoro et al., Appl Sci 12:4496, 2022; Aleem et al., Sci Rep 6:31724, 2016). These biophysical interventions activate critical osteogenic pathways, such as Wnt/β-catenin and MAPK, by modulating intracellular calcium flux and upregulating gene expression, thereby fostering robust bone formation at the implant interface. Cutting-edge innovations, such as piezoelectric feedback implants and AI-optimized stimulation protocols, introduce personalized, self-regulating solutions, particularly beneficial for high-risk patients with conditions like osteoporosis or diabetes. Clinically, bioelectrical stimulation extends its utility to pain management, optimization of immediate-load implants, and enhanced osseointegration in compromised bone, with preclinical and clinical evidence underscoring its efficacy. Looking forward, this chapter explores emerging directions, including multimodal stimulation strategies, genetic profiling for tailored therapies, and the integration of advanced biomaterials. By synthesizing bioengineering, electrophysiology, and clinical practice, bioelectrical stimulation is a promising adjunct to implantology—preclinical data and small clinical trials show improved early osseointegration metrics, but larger randomized studies are needed before routine clinical adoption can be recommended.