Facial reconstruction following skin cancer ablation combines surgical innovation with aesthetic precision, aiming not only to remove malignancy but also to restore both appearance and function. This chapter highlights the significance of facial subunits and the careful selection of reconstructive materials that closely match the excised tissue. It explores reconstructive strategies for basal cell carcinoma (BCC) and squamous cell carcinoma (SCCa), the most common nonmelanoma skin cancers. Through a multidisciplinary approach involving dermatologists, oncologists, and surgeons, the discussion spans from local flaps to complex microvascular tissue transfers. The ultimate goal is to achieve oncologic control while optimizing cosmetic and functional outcomes, thereby enhancing the patient’s quality of life.