Bioanalytical Assays: Gas Chromatography (GC)
摘要
The quantitative determination of analytes in biological matrices such as blood and urine is called bioanalysis. Bioanalysis regulatory authorities and International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) guidance requires that the concentration-time profiles of drugs and/or metabolites in man or in animals are studied so their respective pharmacokinetics can be calculated and used as a basis for the evaluation of preclinical (especially toxicological) and clinical studies.