Gender stands out as a strong determinant of health, especially for trans and gender-diverse people, who are at greater risk of suffering from mental health problems than the cisgender population and the rest of the LGBTIQ+ community. In addition, this is made invisible both in social reality and in scientific reality, where existing studies in mental health are framed in binary and biologist parameters. Thus, from a biopsychosocial perspective, a feminist epistemology applied to sociology, a decolonial gender perspective, and a depathologising perspective of trans identities, this research aims to generate space, through life story interviews, to the lived experience of trans and gender-diverse people as service users of mental health care services in Barcelona, seeing if the latter constitute a space of alienation or help for people from the collective.