Numerical Study of a Miniature Concentration Gradient Generators (CGGs) of Various Shapes

Microfluidic devices in the miniaturized chip format are famous for performing laboratory functions and are used in a wide array of biomedical applications such as rapid clinical diagnosis, forensic science, flow cytometry, and analysis of blood chemistry, protein and DNA. In many biochemical applications studies of CGG helps to get the trends of cells and molecules in different samples such as extracting the maximum information of tumour cells in response to several drugs varying in concentration so as to obtain the minimal sample which is helpful for basic biomedical research in cancer treatment. This paper analyses concentration gradient generators (CGGs) of various shapes having two inlets and five outlets for water and ethanol fluids. The study resulted that the square-shaped CGG performed better than the other designs. It also demonstrates the no significant effect of Reynold number variation on the concentration gradient for Straight CGG.