Current Advances in Tablet in Tablet as Drug Delivery System: A Review

Tablets are the most frequently used oral dosage form amongst the patient because of their simplicity, accuracy in the administration of dose, stability, and economy. Coating of the tablet is one of the most important techniques to mask the bitter taste, unpleasant odor and also for a better quality of tablets like color and texture. Commonly used coating techniques are aqueous or organic coating which has its limitations. As compared to other coating techniques tablet in tablet (Compression coating) is one of the first non-solvent coating techniques and it is also known as a dry coating or press coating. The present review consolidates and broadens on introduction, classification, recent advancement, and characterization of tablet in tablet technology. The one-step dry coating (OSDrC®) technology which is used to manufacture tablet in tablet is based on three compression processes. It does not require a separate procedure for the production of the core tablet as both the layer (core layer and surrounding compressed coating layer) are formed into the same tablet press on one turret. Compression coating technology is not only used to preserve the drug from the atmosphere but also to attain the desired release of the drug at a specific site.