Treating Fungal Infections by Herbal Transdermal Patches
摘要
Innovations in transdermal drug delivery system (TDDS) have made important contributions to medical practice by providing advances in the delivery of treatment with existing and novel drugs. Today about 74% of drugs are taken orally and are found not to be as effective as desired. To improve such character transdermal drug delivery system was emerged. Drug delivery through the skin to achieve a systemic effect of a drug is commonly known as transdermal drug delivery system. The study aimed to formulate herbal transdermal patch and to evaluate its physicochemical properties. The Herbal transdermal patch was formulated by adding the extract of neem in the form of oil and ginger powder. Physiochemical tests viz. visual inspection, pH, thickness, weight variation, folding endurance etc. were performed to determine overall efficiency of patches. The antifungal efficacy was investigated with marketed antifungal patch and found reasonably comparable. The related parameters also were estimated in specified limits.