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From Radioimmunodetection to Radiomolecular Precision Oncology Via Radionanotargeting by Intelligent Multidisciplinary Radiotheragnostic Nanoparticles

  • Kalevi Kairemo

摘要

This chapter describes briefly some scientific activities common to Richard P. Baum and Kalevi Kairemo. Both started with radioimmunodetection in late 1980s and ended up with radiomolecular precision oncology in 2020s. The author also had own interests which Richard Baum did not touch. The author worked some time with oligonucleotide radionuclide therapy (radionanotargeting) in the 1990s learning that it will be impossible in clinical practice. On the contrary, in spite of his own scepticism, intelligent multidisciplinary targeted nanoparticles could be constructed although being cumbersome. Here radiotheragnostic compounds will play major role. Additionally, some personal aspects are presented in order to honour Richard Baum’s achievements.