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Functionalized Carbon Nanostructures for Bone Tissue Engineering

  • Shubhashree Das,
  • Binapani Barik,
  • Gurudutta Pattnaik,
  • Kalim Deshmukh,
  • Srikanta Moharana

摘要

Functionalized carbon nanostructures (FCNs) can potentially significantly transform the area of bone tissue engineering. FCNs, including carbon nanotubes (CNTs) and graphene, possess significant mechanical characteristics, a considerable surface area, and the ability to modify surface chemistry through functionalization. This chapter examines the many functions of FCNs in bone tissue engineering, focusing on their ability to tackle significant obstacles in bone regeneration and repair. FCNs have specific characteristics that make them well-suited for interacting with biological systems. Their adjustable surface chemistry allows for precise manipulation of interactions with cells and biomolecules, facilitating cell adhesion, proliferation, and differentiation, which are crucial for successful bone regeneration. Furthermore, FCNs demonstrate exceptional biocompatibility, guaranteeing low negative impacts on tissues. FCNs can be utilized as reinforcements in scaffold-based methods for bone tissue creation to improve the mechanical characteristics of the scaffold. Integrating FCNs into scaffolds enhances their strength, rigidity, and resilience, offering structural reinforcement for cellular growth and tissue development. Furthermore, FCNs can serve as vehicles for bioactive molecules or therapeutic agents, allowing for precise release and targeted distribution to improve the processes of bone regeneration. Functionalized carbon nanostructures (FCNs) have the potential to enhance bone tissue engineering methods by providing bioelectrical stimulation. These electrical signals control cellular activity and tissue formation, improving osteogenic differentiation and speeding healing. Continued research can transform the therapy of bone injuries, deformities, and disorders.